November 20, 2025
Partnerships

Safe and Hypernative Partner to Bring Enterprise-Grade Security to Multisig

The world's leading multisig now comes with built-in threat detection and policy enforcement, delivering institutional-grade protection for more than $65B in assets

Hypernative

The world’s leading multisig just got safer. Safe and Hypernative announced a strategic partnership that embeds Hypernative real-time threat detection and policy enforcement engine directly into Safe’s multisig experience, enabling teams to automatically detect, explain, and prevent malicious or non-compliant transactions before they execute onchain.

The collaboration, announced at Devconnect Buenos Aires, marks the industry’s first natively-integrated transaction security layer, combining Safe’s battle tested multisig infrastructure with Hypernative Guardian, the company’s pre-transaction simulation and policy-enforcement engine that delivers real-time, AI-driven risk detection and automated protection for every transaction.

The partnership arrives at a critical moment for Web3. As digital assets move from early adopters to mainstream institutions, the ecosystem faces mounting losses from exploits, phishing, and operational errors with more than $9.3B last year alone. With billions now flowing through programmable smart accounts, organizations are demanding stronger, more automated safeguards that match the pace and complexity of modern digital-asset operations. The Safe-Hypernative collaboration answers that call, evolving multisig security from shared access control to continuous, intelligent protection built directly into transaction execution.

Embedding Hypernative directly into Safe marks the next era of onchain asset protection. For years, Safe has set the standard for transparent, secure digital ownership. Now, with Guardian built into every transaction flow, we’re elevating that standard, giving every organization the ability to operate with institutional security by default.

Rahul Rumalla, CEO @ Safe Labs

How It Works


Hypernative Guardian is now accessible directly within the Safe interface, giving treasury, compliance, and security teams deep visibility into every transaction before signing. The integration delivers four core capabilities:

Real-time risk assessment screens every transaction in your Safe queue against over 300 risk types, including contract exploits, phishing, fraud, and compliance violations, before any signer approves it.

Automatic simulation and risk explanation shows exactly what will happen when a transaction executes. No more blind signing of complex DeFi interactions. Guardian breaks down the intent, outcome, and risks in plain language.

Custom enforcement policies let teams encode their complete risk framework into automated rules. Treasury teams can restrict deposits to whitelisted protocols and cap swap slippage. Asset managers can screen for sanctioned addresses and pool toxicity thresholds. Protocol teams can require manual approval for contract upgrades.

Interactive approval flow surfaces all risk assessments directly in Safe's interface, powered by Hypernative's AI-based detection engines. When Guardian flags a transaction, signers see clear explanations and can make informed decisions without leaving Safe.

This isn't security bolted onto Safe. It's security embedded into every transaction flow.

Safe redefined how organizations coordinate onchain. Together, we’re redefining how they protect their assets. With Guardian built into Safe workflow, teams no longer have to choose between speed, usability, and security.

Gal Sagie, Co-Founder and CEO @ Hypernative

Built for Institutional Operations

The integration serves the specific needs of organizations managing serious digital asset operations:

DAO and protocol treasuries managing community funds get automated threat detection with custom policies that balance protection and governance velocity. Define your spending limits, whitelisted protocols, and counterparty restrictions once. Guardian enforces them automatically.

Asset managers and institutional funds securing client capital across complex DeFi strategies get compliance-ready audit trails, real-time risk visibility, and the enterprise-grade security that institutional LPs demand. Every transaction includes documentation of the risks assessed and policies applied.

Exchanges and market makers protecting large asset vaults get predictive threat detection that often identifies exploits minutes before the first malicious transaction. Cross-chain coverage spans 70+ blockchain networks with 99.8% detection accuracy and just 0.001% false positives.

Organizations like Ethena have been using both Guardian and Safe to protect their operations, but as separate systems. With this integration, teams that previously had to manage security alongside their multisig workflow now get both in a unified experience without sacrificing Safe's non-custodial benefits or requiring teams to learn new tools.

We integrated Guardian to protect billions in transactions across our $10B ecosystem. Having that same protection now embedded directly in Safe means teams don't have to choose between security and operational velocity. This is what institutional-grade Web3 infrastructure looks like: security native to the workflow, not bolted onto it.

Guy Young, Founder @ Ethena

Read more: Ethena Turns to Hypernative to Protect Transactions Across Its Ecosystem

Available Now

Organizations can access Guardian's protection starting today. Visit safe.global/safeshield to learn more or contact your Safe account representative to get started. Existing Hypernative Guardian customers can now manage all security configuration through the Safe interface for a unified experience.

About Safe

Safe (previously Gnosis Safe) is an onchain asset custody protocol, securing ~$60B in assets today. Released as on open-source software stack by the Safe Ecosystem Foundation, it is establishing a universal ‘smart account standard for secure custody of digital assets, data, and identity. Safe is built for the mission to unlock digital ownership for everyone in web3, including DAOs, enterprises, retail, and institutional users

Website, Twitter, Discord, Blog, GitHub, Docs

About the Safe Ecosystem Foundation, Zug, Switzerland

The mission of the Safe Ecosystem Foundation is to support the development of Safe, to strengthen Safe technology and to promote the Safe Ecosystem. The Safe Ecosystem is a non-profit organization based in Zug, Switzerland, that helps educate people about Safe smart accounts and promotes Safe technology through the provision of grants and other forms of funding. 

Legal Disclaimer

This is not an offer to sell or a solicitation of an offer to purchase any SAFE tokens and is not an offering, advertisement, solicitation, confirmation, statement, or any financial promotion that can be construed as an invitation or inducement to engage in any investment activity or similar. 

The Safe Ecosystem Foundation makes no representations, warranties and/or covenants with respect to the Safe Technology (or any implementations of the Safe{Wallet} and/or Safe Smart Accounts) or any program (Grants, Hackathons and/or any other forms of funding) run by the Safe Ecosystem Foundation. You should not rely on the content herein for advice of any kind, including legal, investment, financial, tax, or other professional advice, and such content is not a substitute for advice from a qualified professional.

About Hypernative


Hypernative is a real-time monitoring, risk detection, and automated response solution trusted by over 250 clients, including industry leaders like Circle, Ethena, Galaxy Digital, OKX, and Wintermute. Our platform accurately identifies over 300 risk types with a 99.8% detection rate and an exceptionally low false positive rate of just 0.001%, providing precious minutes to respond before damage occurs. Hypernative actively secures over $100B in digital assets across 70+ blockchains, having already saved $2B in funds from hacks, exploits, and fraud.

Reach out for a demo of Safe Shield x Hypernative, tune into Hypernative’s blog and our social channels to keep up with the latest on cybersecurity in Web3.

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